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By understanding and exploiting the biology of life, biotechnology advances medicine, biopharmaceuticals, agriculture, and industrial biotechnology, addressing global challenges through cutting-edge scientific discovery. The Institute of Systems, Molecular and Integrative Biology (ISMIB) was established to integrate cutting-edge and clinical research across the Faculty of Health and Life Sciences. Programmes of work across ISMIB are varied and are led by world experts in their fields. Our biotechnology research combines systems-based studies, including multiomics, data analysis, structural biology, synthetic biology, and artificial intelligence, supported by top-tier research facilities and our commitment to sharing discoveries. Integrating molecular biology, genetic engineering and biochemical engineering across a variety of biomolecules, the focus of our research ranges from nucleic acids to saccharides and proteins. We also explore cellular chemistry across microorganisms and complex organisms, in both healthy and diseased states, and integrate artificial intelligence-based approaches to evolving and studying the molecules of life. We offer intensive PhD programmes with exposure to diverse biotechnologies. Research is multidisciplinary, with strong collaborations across the Institute and wider University, spanning physical, chemical, and clinical sciences. Technologies include electrophysiology, biosensors, protein engineering and expression, proteomics, transcriptomics, NMR, X-ray crystallography, enzyme assays, confocal microscopy, nanoparticles, protein modelling, and molecular biology.
